Metabolic and hormonal disorders

Hypothyroidism

Symptoms of Hypothyroidism

  • Chronic fatigue and drowsiness
  • Unexplained weight gain
  • Dry and pale skin
  • Increased sensitivity to cold
  • Constipation
  • Depression or mood disorders
  • Slow heart rate
  • Brittle hair, hair loss
  • Heavy or irregular menstrual periods in women
  • Swollen face and hoarse voice

Treatment of Hypothyroidism

  • Hormone replacement therapy with levothyroxine (synthetic T4)
  • Regular monitoring of TSH levels (thyroid-stimulating hormone)
  • Dosage adjustment according to patient needs
  • Lifelong medical follow-up in most cases
  • Patient education on the importance of treatment adherence

📌 Summary

Definition: Hypothyroidism is a condition characterized by insufficient production of thyroid hormones by the thyroid gland. This slows down the body's metabolism and can affect many bodily systems.
Affected population: Mainly women over 40 years old, but it can occur at any age, including in newborns.
Common causes: Autoimmune disease (Hashimoto's thyroiditis), thyroid removal, radioactive iodine treatment, iodine deficiency, side effects of certain medications (lithium, amiodarone).

Prevention of Hypothyroidism

  • Adequate iodine intake (iodized salt, seafood)
  • Medical monitoring in case of family history of thyroid diseases
  • Regular thyroid function checks for at-risk individuals (women, elderly, postpartum)
  • Avoid prolonged nutritional deficiencies
  • Inform patients about side effects of certain medications affecting the thyroid

Hyperthyroidism

Symptoms of Hyperthyroidism

  • Weight loss despite normal or increased appetite
  • Tachycardia (increased heart rate)
  • Restlessness, nervousness, or irritability
  • Excessive sweating and heat intolerance
  • Hand tremors
  • Fatigue, often with insomnia
  • Increased bowel movements (mild diarrhea)
  • Irregular menstrual cycle in women
  • Hair loss and thin skin
  • Exophthalmos (protruding eyes), especially in Graves' disease

Treatment of Hyperthyroidism

  • Antithyroid medications (carbimazole, propylthiouracil)
  • Radioactive iodine treatment to partially destroy the thyroid gland
  • Thyroid surgery (partial or total thyroidectomy)
  • Beta-blockers to control symptoms (palpitations, tremors)
  • Regular medical follow-up and treatment adjustment based on response

📌 Summary

Definition: Hyperthyroidism is a condition in which the thyroid gland produces an excessive amount of thyroid hormones, thereby accelerating the body's metabolism and causing various symptoms.
Affected Population: Mainly women between 20 and 50 years old, although men and older adults can also be affected.
Common Causes: Graves' disease (the most frequent autoimmune cause), functioning thyroid nodules, thyroiditis, iodine excess, excessive intake of thyroid hormones.

Prevention of Hyperthyroidism

  • Monitoring individuals at risk (family history or autoimmune diseases)
  • Avoiding excessive iodine intake from diet or uncontrolled supplements
  • Monitoring side effects of medications that may stimulate the thyroid
  • Early diagnosis and management of thyroid nodules
  • Regular thyroid function check-ups in pregnant or postpartum women

Metabolic syndrome

Symptoms of Metabolic Syndrome

  • High waist circumference (abdominal obesity)
  • High blood pressure
  • Elevated fasting blood sugar levels
  • High triglyceride levels
  • Low HDL cholesterol ("good" cholesterol) levels
  • Frequent fatigue
  • Progressive weight gain, especially around the abdomen
  • Signs of insulin resistance (e.g., acanthosis nigricans)

Treatment of Metabolic Syndrome

  • Weight loss through an appropriate diet
  • Regular physical activity (at least 30 minutes per day)
  • Treatment of high blood pressure
  • Management of diabetes or elevated blood sugar levels
  • Correction of lipid disorders (triglycerides, cholesterol)
  • Comprehensive medical follow-up to prevent cardiovascular complications

📌 Summary

Definition: Metabolic syndrome is a group of associated metabolic disorders that significantly increase the risk of cardiovascular disease and type 2 diabetes. It includes high blood pressure, high blood sugar, excess abdominal fat, and abnormal cholesterol or triglyceride levels.
Affected population: Mainly overweight or obese adults, especially those over 40. The risk increases with age and a sedentary lifestyle.
Common causes: Poor diet, lack of physical activity, insulin resistance, family history of diabetes or cardiovascular disease, and chronic stress.

Prevention of Metabolic Syndrome

  • Maintain a healthy weight through a balanced diet
  • Avoid ultra-processed foods high in sugar and fat
  • Engage in regular physical activity
  • Monitor blood pressure, weight, and blood sugar regularly
  • Reduce alcohol and tobacco consumption
  • Undergo regular metabolic check-ups for at-risk individuals

Morbid obesity

Symptoms of Morbid Obesity

  • Body Mass Index (BMI) over 40
  • Shortness of breath with minimal effort
  • Chronic fatigue
  • Joint pain (knees, back, etc.)
  • Difficulty moving or performing daily activities
  • Snoring or sleep apnea
  • Digestive issues or acid reflux
  • Psychological problems: isolation, low self-esteem, depression

Treatment of Morbid Obesity

  • Medically supervised weight loss program
  • Personalized diet plan by a dietitian
  • Regular and appropriate physical activity
  • Behavioral or psychological therapy
  • Appetite or metabolism control medications (under medical supervision)
  • Bariatric surgery (gastric band, sleeve, bypass) in selected cases
  • Long-term medical follow-up

📌 Summary

Definition: Morbid obesity is a severe form of obesity defined by a body mass index (BMI) over 40, or over 35 with associated complications. It poses a major risk to both physical and mental health.
Affected population: Adults and adolescents, mainly in urban or high-income areas. Women are sometimes more affected depending on cultural and socioeconomic contexts.
Common causes: Unbalanced diet, sedentary lifestyle, genetic factors, hormonal disorders, chronic stress, eating disorders, and obesogenic environments.

Prevention of Morbid Obesity

  • Nutritional education from an early age
  • Balanced diet with portion control
  • Limit intake of sugary, fatty, and processed foods
  • Maintain regular physical activity (at least 150 minutes per week)
  • Monitor body mass index (BMI) regularly
  • Address overweight issues early to prevent progression to severe obesity

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