Diseases of the immune system

Lupus

Symptoms of Lupus

  • Chronic fatigue
  • Joint pain or swelling
  • Skin rashes, especially a butterfly-shaped rash on the face
  • Unexplained fever
  • Hair loss
  • Photosensitivity (abnormal reaction to sunlight)
  • Chest pain when breathing
  • Frequent mouth ulcers
  • Kidney or neurological problems in severe cases

Treatment of Lupus

  • Non-steroidal anti-inflammatory drugs (NSAIDs) to relieve pain
  • Corticosteroids to reduce inflammation
  • Antimalarial drugs such as hydroxychloroquine
  • Immunosuppressants in severe cases
  • Regular monitoring of organs (kidneys, heart, nervous system)
  • Adjustment of treatment according to disease progression
  • Psychological support in case of fatigue or depression

📌 Summary

Definition: Lupus is a chronic autoimmune disease in which the immune system attacks healthy tissues, causing widespread inflammation. It can affect the skin, joints, kidneys, heart, lungs, and other organs.
Affected population: Mainly women between 15 and 45 years old, with higher prevalence among people of African, Asian, and Latin American descent.
Common causes: Genetic predisposition, hormonal imbalances, viral infections, sun exposure, certain medications, intense stress.

Prevention and Management of Lupus

  • Avoid prolonged sun exposure
  • Regular medical follow-up to adjust treatments
  • Adopt a healthy lifestyle (balanced diet, sufficient rest)
  • Avoid excessive stress
  • Inform family and close friends about the disease
  • Avoid self-medication

Rheumatoid arthritis

Symptoms of Rheumatoid Arthritis

  • Persistent joint pain
  • Swelling and stiffness of the joints, especially in the morning
  • Significant and general fatigue
  • Loss of appetite and weight loss
  • Redness and warmth around the joints
  • Symptoms on both sides of the body (bilateral involvement)
  • Rheumatoid nodules under the skin in advanced cases

Treatment of Rheumatoid Arthritis

  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Corticosteroids to quickly reduce inflammation
  • Disease-modifying treatments (methotrexate, sulfasalazine, etc.)
  • Biotherapies targeting the immune system
  • Physiotherapy and exercises to maintain joint mobility
  • Specialized medical follow-up in rheumatology
  • Surgery in cases of severe deformity

📌 Summary

Definition: Rheumatoid arthritis is a chronic inflammatory autoimmune disease that mainly affects the joints, causing pain, swelling, and stiffness. It can also affect other organs such as the eyes, lungs, or heart.
Affected population: Mainly women aged 30 to 60, but it can also occur earlier or later.
Common causes: Genetic predisposition, immune system dysfunction, environmental factors (smoking, viral infections), hormonal imbalances.

Prevention and Management of Rheumatoid Arthritis

  • Early diagnosis and prompt treatment to limit damage
  • Avoid smoking, a known aggravating factor
  • Adopt an anti-inflammatory diet (fruits, vegetables, omega-3)
  • Maintain appropriate physical activity
  • Regular monitoring of treatment side effects
  • Psychological support if needed (fatigue, chronic pain)

Multiple sclerosis

Symptoms of Multiple Sclerosis

  • Severe chronic fatigue
  • Visual problems (blurred vision, eye pain, double vision)
  • Numbness, tingling, or prickling sensations
  • Balance and coordination problems
  • Muscle weakness or partial paralysis
  • Urinary or bowel problems
  • Cognitive issues and memory troubles
  • Symptoms vary depending on flare-ups

Treatment of Multiple Sclerosis

  • Treating flare-ups with corticosteroids
  • Long-term medications to reduce flare-up frequency (interferons, monoclonal antibodies, etc.)
  • Medications for symptoms like fatigue, spasticity, or pain
  • Physical therapy with a physiotherapist
  • Psychological support and cognitive therapies
  • Regular neurological follow-up

📌 Summary

Definition: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. It is characterized by the progressive destruction of myelin, the protective sheath around nerves, leading to various motor, sensory, and cognitive disorders.
Affected population: Mainly young adults aged 20 to 40, with a higher prevalence in women.
Common causes: Multifactorial origin: genetic predisposition, viral infections (especially Epstein-Barr), vitamin D deficiency, smoking, and environmental factors.

Prevention and Management of Multiple Sclerosis

  • There is no known specific prevention for the disease
  • Reduce risk factors: avoid smoking, maintain a healthy lifestyle
  • Follow treatments to limit flare-ups
  • Moderate and adapted physical activity to preserve mobility
  • Prevention of complications (urinary infections, pressure sores, etc.)
  • Patient education for better autonomy

Various autoimmune diseases

Symptoms of Various Autoimmune Diseases

  • Persistent and unexplained fatigue
  • Chronic muscle or joint pain
  • Skin rashes or red patches
  • Recurrent mild fever
  • Digestive problems or loss of appetite
  • Inflammation of specific organs (thyroid, kidneys, skin, etc.)
  • Neurological symptoms (numbness, cognitive issues)
  • Symptoms vary depending on the organ targeted by the autoimmune response

Treatment of Various Autoimmune Diseases

  • Immunosuppressive drugs (corticosteroids, methotrexate, etc.)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief
  • Targeted treatment depending on the affected organ (insulin, hormones, etc.)
  • Plasmapheresis in severe cases
  • Psychological support and multidisciplinary care
  • Rehabilitation or physical therapy if there is functional impairment

📌 Summary

Definition: Autoimmune diseases are a group of disorders in which the immune system mistakenly attacks the body’s healthy cells. They can affect one or multiple organs or systems, such as the skin, joints, glands, or nerves.
Affected population: Mainly women between 20 and 50 years old, although men and children can also be affected depending on the disease.
Common causes: Genetic factors, viral or bacterial infections, hormonal imbalances, chronic stress, smoking, and exposure to certain chemicals or medications.

Prevention and Follow-up of Various Autoimmune Diseases

  • There is no specific prevention for these diseases
  • Avoid known triggering factors (infections, stress, sun exposure, etc.)
  • Healthy lifestyle: balanced diet, gentle physical activity
  • Regular medical follow-up and adherence to treatments
  • Patient education to recognize signs of flare-ups
  • Vaccination adapted according to immune status

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