Alzheimer’s disease and dementia
Definition: Alzheimer's disease is a common form of progressive dementia that affects memory, reasoning, language, and autonomy. It causes progressive deterioration of cognitive functions due to degeneration of brain cells.
Affected population: Mainly people over 65 years old, although early-onset forms can occur before age 60. Women are slightly more affected than men.
Common causes: Advanced age, genetic predisposition (APOE-e4 gene), previous head injuries, cardiovascular diseases, low educational level, social isolation, sedentary lifestyle, unbalanced diet.
Stroke
Definition: A stroke (cerebrovascular accident) is a sudden interruption of blood flow to a part of the brain, caused either by a clot (ischemic stroke) or by bleeding (hemorrhagic stroke). It leads to the death of brain cells deprived of oxygen.
Population affected: Mainly adults over 55 years old, but it can also occur in younger people. Men are slightly more affected, although women often experience more severe forms.
Common causes: High blood pressure, diabetes, smoking, high cholesterol, atrial fibrillation, obesity, sedentary lifestyle, family history of stroke.
Parkinson’s disease
Definition: Parkinson's disease is a chronic progressive neurological disorder that affects the central nervous system. It is mainly characterized by movement disorders (tremors, muscle rigidity, slowness) caused by the degeneration of dopamine-producing neurons in the brain.
Affected population: Mainly people over 60 years old, although it can appear earlier in some cases (early-onset form). It affects both men and women, with a slight male predominance.
Common causes: Exact causes are unknown, but genetic factors, exposure to environmental toxins, family history, and aging are suspected in its development.
Epilepsy
Definition: Epilepsy is a chronic neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain. These seizures may manifest as convulsions, loss of consciousness, or unusual sensations.
Affected population: It can affect anyone at any age, but is more common in children, adolescents, and elderly people.
Common causes: Brain injuries (head trauma, stroke), nervous system infections (meningitis, encephalitis), congenital abnormalities, brain tumors, genetic factors, or sometimes no identifiable cause (idiopathic epilepsy).
Multiple sclerosis
Definition: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, where the immune system attacks the protective sheath of the nerves (myelin), disrupting communication between the brain and the rest of the body.
Affected population: Mainly young adults between 20 and 40 years old, with a predominance in women.
Common causes: Exact causes remain unknown, but several factors may be involved: genetic predisposition, viral infections, environmental factors (vitamin D deficiency, smoking), and immune system dysregulation.
Amyotrophic lateral sclerosis (ALS)
Definition: Amyotrophic lateral sclerosis (ALS), also known as Charcot disease, is a severe neurodegenerative disease that affects motor neurons responsible for controlling voluntary muscles, leading to progressive paralysis.
Affected population: Mainly adults between 40 and 70 years old, with a slight male predominance. Rare in young people.
Common causes: In most cases, the cause is unknown (sporadic form), but about 5 to 10% are genetic in origin (familial form). Other possible factors include oxidative stress, glutamatergic imbalances, environmental toxins, and genetic mutations.
Coma and traumatic brain injuries
Definition: Coma is a state of deep and prolonged unconsciousness caused by severe brain injury. It can result from traumatic brain injuries, strokes, infections, or intoxications. Traumatic brain injuries (TBI) specifically refer to damage to the brain caused by a direct or indirect impact to the head.
Affected Population: All age groups can be affected, with a higher incidence among young adults (traffic accidents, violent sports) and the elderly (falls).
Common Causes: Traffic accidents, falls, assaults, head trauma, stroke, oxygen deprivation (hypoxia), drug overdose, brain infections (encephalitis, meningitis).
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